Spinal Gabapentin and Antinociception: Mechanisms of Action

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Spinal gabapentin and antinociception: mechanisms of action.

Spinal gabapentin has been known to show the antinociceptive effect. Although several assumptions have been suggested, mechanisms of action of gabapentin have not been clearly established. The present study was undertaken to examine the action mechanisms of gabapentin at the spinal level. Male SD rats were prepared for intrathecal catheterization. The effect of gabapentin was assessed in the fo...

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Background and Objective: Evidence about the effect of theophylline and gabapentin on post-spinal headache is rare. Therefore, in this study, we compared the effect of gabapentin and theophylline on post-spinal headache after cesarean section. Materials and Methods: We conducted a double-blind randomized clinical trial on 120 pregnant women, who underwent spinal anesthesia due to cesarean sect...

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ژورنال

عنوان ژورنال: Journal of Korean Medical Science

سال: 2003

ISSN: 1011-8934,1598-6357

DOI: 10.3346/jkms.2003.18.2.255